ElectroPen: An ultralow-cost piezoelectric electroporator

Electroporation is a powerful alternative to heat shock for delivering small molecules such as plasmids across cell membranes.  By application of an electrical field netivetly charged DNA is forced into elector-competent cells by an electrohoresis-type effect. Electroporators can be expensive, generally over $2000, hence the popularity of more chemical solutions such as heat shock. Enter […]

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A Blueprint for Cost-Efficient Localization Microscopy

This paper, “A Blueprint for Cost-Efficient Localization Microscopy,” write it’s own summary better than we ever could: “In this study, we questioned every technical high-end component used in standard localization microscopes to reduce the total cost of a wide-field setup and to ensure continued single-molecule sensitivity. We demonstrate that localization microscopy with subdiffraction resolution on […]

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